Carbon Nanotube-DNA Nanoarchitectures and Electronic Functionality

Biological molecules such as deoxyribonucleic acid (DNA) possess inherent recognition and self‐assembly capabilities, and are attractive templates for constructing functional hierarchical material structures as building blocks for nanoelectronics. Here we report the assembly and electronic functionality of nanoarchitectures based on conjugates of single‐walled carbon nanotubes (SWNTs) functionalized with carboxylic groups and single‐stranded DNA (ssDNA) sequences possessing terminal amino groups on both ends, hybridized together through amide linkages by adopting a straightforward synthetic route. Morphological and chemical‐functional characterization of the nanoarchitectures are investigated using scanning electron microscopy, transmission electron microscopy, atomic force microscopy, energy‐dispersive X‐ray spectroscopy, Raman spectroscopy, and Fourier‐transform infrared spectroscopy. Electrical measurements (I–V characterization) of the nanoarchitectures demonstrate negative differential resistance in the presence of SWNT/ssDNA interfaces, which indicates a biomimetic route to fabricating resonant tunneling diodes. I–V characterization on platinum‐metallized SWNT–ssDNA nanoarchitectures via salt reduction indicates modulation of their electrical properties, with effects ranging from those of a resonant tunneling diode to a resistor, depending on the amount of metallization. Electron transport through the nanoarchitectures has been analyzed by density functional theory calculations. Our studies illustrate the great promise of biomimetic assembly of functional nanosystems based on biotemplated materials and present new avenues toward exciting future opportunities in nanoelectronics and nanobiotechnology. Single‐stranded DNA (ssDNA) sequences with terminal amino groups and single‐walled carbon nanotubes (SWNTs) functionalized with carboxylic groups can be conjugated through amide linkages (see image). These nanoarchitectures exhibit negative differential resistance, which indicates a biomimetic route to the fabrication of resonant tunneling diodes. The electrical properties are modulated by metallization.