Erythrocyte ion transport in rats subjected to acute and chronic hypobaric hypoxia

Our study addresses selected parameters of rat erythrocyte ion transport (Na(+)-K(+) pump, Na(+)-K(+)-2Cl- cotransport, and passive cation fluxes) after acute or chronic hypoxia exposure. We did not find any significant change of ion transport after acute hypoxia. However, chronic hypoxia could modi...

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Veröffentlicht in:	Physiological research 2006-01, Vol.55 (6), p.711-713
Hauptverfasser:	Rauchová, H, Vokurková, M, Dobesová, Z, Kunes, J, Zicha, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Age Factors Aging - metabolism Altitude Animals Changes Chronic Disease Erythrocytes Erythrocytes - metabolism Hypoxia Hypoxia - metabolism Ion Transport Potassium - metabolism Rats Rats, Wistar Rodents Sodium - metabolism Sodium-Potassium-Chloride Symporters - metabolism Sodium-Potassium-Exchanging ATPase - metabolism
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Beschreibung
Zusammenfassung:	Our study addresses selected parameters of rat erythrocyte ion transport (Na(+)-K(+) pump, Na(+)-K(+)-2Cl- cotransport, and passive cation fluxes) after acute or chronic hypoxia exposure. We did not find any significant change of ion transport after acute hypoxia. However, chronic hypoxia could modify ion transport because the affinity of Na(+)-K(+) pump for intracellular Na(+) seems to be decreased.
ISSN:	0862-8408 1802-9973
DOI:	10.33549/physiolres.930988