Acute lumen overdilation improves outcome after brachytherapy of in-stent restenosis

The aim of our study was to test the impact of acute lumen overdilation on neointimal hyperplasia and late lumen size after vascular brachytherapy for in-stent restenosis (ISR). Forty-seven ISR lesions located in 47 coronary arteries in 44 consecutive patients underwent beta brachytherapy with seria...

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Veröffentlicht in:	Cardiovascular revascularization medicine 2006-10, Vol.7 (4), p.202-207
Hauptverfasser:	Witkowski, Adam, Kalińczuk, Łukasz, Chmielak, Zbigniew, Pręgowski, Jerzy, Łyczek, Jarosław, Kawczyńska, Maria, Bulski, Wojciech, Kulik, Anna, Pszona, Stanisław, Kępka, Cezary, Przyłuski, Jakub, Owczarczyk, Jacek, Rużyłło, Witold
Format:	Artikel
Sprache:	eng
Schlagworte:	Angioplasty, Balloon Brachytherapy - methods Coronary Angiography Coronary Restenosis - diagnostic imaging Coronary Restenosis - radiotherapy Coronary Restenosis - therapy Dilatation, Pathologic Female Humans Hyperplasia In-stent restenosis Intravascular ultrasound Linear Models Lumen overdilatation Male Middle Aged Recurrence Retrospective Studies Stents Treatment Outcome Tunica Intima - diagnostic imaging Tunica Intima - pathology Tunica Intima - radiation effects Ultrasonography, Interventional Vascular brachytherapy
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Zusammenfassung:	The aim of our study was to test the impact of acute lumen overdilation on neointimal hyperplasia and late lumen size after vascular brachytherapy for in-stent restenosis (ISR). Forty-seven ISR lesions located in 47 coronary arteries in 44 consecutive patients underwent beta brachytherapy with serial intravascular ultrasound studies. Vessel, lumen, and stent cross-sectional area were measured at 1-mm steps. Based on an interpolated reference cross-sectional area, each cross section was assessed as overdilated (lumen cross-sectional area >interpolated reference cross-sectional area) or not overdilated (lumen cross-sectional area
ISSN:	1553-8389 1878-0938
DOI:	10.1016/j.carrev.2006.07.006