The Lymphopenic Mouse in Immunology: From Patron to Pariah
A recent surge of interest in the behavior of T and B cells in lymphopenic model systems has resurrected a certain cynicism about the validity of using such models to answer important immunological questions. Here we discuss this skepticism in a broader historical context.
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Veröffentlicht in: | Immunity (Cambridge, Mass.) Mass.), 2006-12, Vol.25 (6), p.851-855 |
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Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | A recent surge of interest in the behavior of T and B cells in lymphopenic model systems has resurrected a certain cynicism about the validity of using such models to answer important immunological questions. Here we discuss this skepticism in a broader historical context. |
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ISSN: | 1074-7613 1097-4180 |
DOI: | 10.1016/j.immuni.2006.12.002 |