Microwave-Assisted Synthesis of New Polysubstituted Dienaminoesters and Their Cyclization to 3-Bromo-2(1H)-Pyridinones

A microwave-assisted, telescoped synthesis, involving a Michael-type addition followed by intramolecular cyclization, provides an effective entry to the polysubstituted 3-bromo-2(1H)-pyridinone core.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of organic chemistry 2006-12, Vol.71 (26), p.9895-9898
Hauptverfasser:	Adams, Jeff, Hardin, Alison, Vounatsos, Filisaty
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Cyclization Esters - chemical synthesis Esters - chemistry Esters - radiation effects Exact sciences and technology Heterocyclic compounds Heterocyclic compounds with only one n hetero atom and condensed derivatives Microwaves Molecular Structure Organic chemistry Preparations and properties Pyridones - chemical synthesis Pyridones - chemistry Pyridones - radiation effects Stereoisomerism
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Beschreibung
Zusammenfassung:	A microwave-assisted, telescoped synthesis, involving a Michael-type addition followed by intramolecular cyclization, provides an effective entry to the polysubstituted 3-bromo-2(1H)-pyridinone core.
ISSN:	0022-3263 1520-6904
DOI:	10.1021/jo0618526