beadarray: R classes and methods for Illumina bead-based data

The R/Bioconductor package beadarray allows raw data from Illumina experiments to be read and stored in convenient R classes. Users are free to choose between various methods of image processing, background correction and normalization in their analysis rather than using the defaults in Illumina...

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Veröffentlicht in:Bioinformatics 2007-08, Vol.23 (16), p.2183-2184
Hauptverfasser: Dunning, Mark J., Smith, Mike L., Ritchie, Matthew E., Tavaré, Simon
Format: Artikel
Sprache:eng
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Zusammenfassung:The R/Bioconductor package beadarray allows raw data from Illumina experiments to be read and stored in convenient R classes. Users are free to choose between various methods of image processing, background correction and normalization in their analysis rather than using the defaults in Illumina's; proprietary software. The package also allows quality assessment to be carried out on the raw data. The data can then be summarized and stored in a format which can be used by other R/Bioconductor packages to perform downstream analyses. Summarized data processed by Illumina's; BeadStudio software can also be read and analysed in the same manner. Availability: The beadarray package is available from the Bioconductor web page at www.bioconductor.org. A user's; guide and example data sets are provided with the package. Contact: md392@cam.ac.uk
ISSN:1367-4803
1460-2059
1367-4811
DOI:10.1093/bioinformatics/btm311