Dual-Mode Nanoparticle Probes for High-Performance Magnetic Resonance and Fluorescence Imaging of Neuroblastoma

Working together: A “core–satellite” hybrid nanoparticle probe provides highly improved fluorescence and magnetic resonance (MR) imaging capabilities through synergistic enhancement of its respective components. These hybrid nanoprobes can be used for dual‐modal fluorescence and MR imaging of neurob...

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Veröffentlicht in:	Angewandte Chemie International Edition 2006-12, Vol.45 (48), p.8160-8162
Hauptverfasser:	Lee, Jae-Hyun, Jun, Young-wook, Yeon, Soo-In, Shin, Jeon-Soo, Cheon, Jinwoo
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line colloids diagnostic agents Fluorescent Dyes - analysis Fluorescent Dyes - chemistry Humans hybrid materials Magnetic Resonance Imaging - methods Molecular Probe Techniques Nanoparticles - analysis Nanoparticles - chemistry Nanotechnology Neuroblastoma - diagnosis NMR imaging Silicon Dioxide - chemistry
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Zusammenfassung:	Working together: A “core–satellite” hybrid nanoparticle probe provides highly improved fluorescence and magnetic resonance (MR) imaging capabilities through synergistic enhancement of its respective components. These hybrid nanoprobes can be used for dual‐modal fluorescence and MR imaging of neuroblastoma with expressed polysialic acids.
ISSN:	1433-7851 1521-3773
DOI:	10.1002/anie.200603052