Dynamic roles for G4 DNA in the biology of eukaryotic cells

Recent advances have made a persuasive case for the existence of G4 DNA in living cells, but what—if any—are its functions? Experiments have established how G4 DNA may contribute to the biology of eukaryotic cells, and genomic analysis has identified new ways in which the potential to form G4 DNA ma...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature structural & molecular biology 2006-12, Vol.13 (12), p.1055-1059
1. Verfasser:	Maizels, Nancy
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry Biological Microscopy Biomedical and Life Sciences Cellular biology Deoxyribonucleic acid DNA DNA - chemistry DNA - genetics DNA - metabolism DNA - ultrastructure DNA Replication Eukaryotic Cells - metabolism Genetic algorithms Genome - genetics Genomics Guanosine - genetics Humans Life Sciences Membrane Biology Molecular biology Molecular structure perspective Physiological aspects Protein Structure Structure Telomere - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Recent advances have made a persuasive case for the existence of G4 DNA in living cells, but what—if any—are its functions? Experiments have established how G4 DNA may contribute to the biology of eukaryotic cells, and genomic analysis has identified new ways in which the potential to form G4 DNA may influence gene regulation and genomic stability. This Perspective highlights those advances and identifies some key open questions.
ISSN:	1545-9993 1545-9985
DOI:	10.1038/nsmb1171