Acute retinal necrosis in an acute leukemia pediatric patient

Acute retinal necrosis (ARN) is a serious condition that can impair vision. It mostly occurs in adult patients, especially those severely immunocompromised, in association with a reactivation of a herpes virus infection. We present a 4 years old patient with high risk acute leukemia, whom during a c...

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Veröffentlicht in:	Revista chilena de infectología 2007-08, Vol.24 (4), p.323-326
Hauptverfasser:	Torres T, Juan P, Concha V, Emma, López G, Juan P, Cofre G, José
Format:	Artikel
Sprache:	spa
Schlagworte:	Antiviral Agents - therapeutic use Chickenpox - complications Chickenpox - diagnosis Chickenpox - drug therapy Child, Preschool Humans Immunocompromised Host Male Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy Retinal Necrosis Syndrome, Acute - diagnosis Retinal Necrosis Syndrome, Acute - drug therapy Retinal Necrosis Syndrome, Acute - virology
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Zusammenfassung:	Acute retinal necrosis (ARN) is a serious condition that can impair vision. It mostly occurs in adult patients, especially those severely immunocompromised, in association with a reactivation of a herpes virus infection. We present a 4 years old patient with high risk acute leukemia, whom during a course of intense chemotherapy acquired chickenpox with visceral involvement that affected the retina, causing unilateral blindness. Varicella-zoster virus was detected by PCR in the vitreous humor, in spite of previous acyclovir treatment. The contralateral vision remained undamaged.
ISSN:	0716-1018