Postprandial hypotension due to a lack of sympathetic compensation in patients with diabetes mellitus

Postprandial hypotension due to a lack of sympathetic compensation in patients with diabetes mellitus

Postprandial hypotension is an important hemodynamic abnormality in diabetes mellitus, but few reports are available on the relationship between autonomic dysfunction and postprandial hypotension. Ten diabetic patients and 10 healthy volunteers were recruited for this study. Postural blood pressure...

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Veröffentlicht in:Acta medica Okayama 2007-08, Vol.61 (4), p.191-197
Hauptverfasser: Tanakaya, Machiko, Takahashi, Natsuki, Takeuchi, Kazufumi, Katayama, Yusuke, Yumoto, Akihisa, Kohno, Kunihisa, Shiraki, Teruo, Saito, Daiji
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Diabetes Mellitus - blood
Diabetes Mellitus - physiopathology
Eating - physiology
Female
Heart Rate - physiology
Humans
Hypotension - blood
Hypotension - physiopathology
Male
Middle Aged
Postprandial Period - physiology
Sympathetic Nervous System - physiopathology
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Zusammenfassung:Postprandial hypotension is an important hemodynamic abnormality in diabetes mellitus, but few reports are available on the relationship between autonomic dysfunction and postprandial hypotension. Ten diabetic patients and 10 healthy volunteers were recruited for this study. Postural blood pressure and heart rate changes were measured before lunch, and then the hemodynamic responses to a standardized meal were investigated. Holter electrocardiogram (ECG) monitoring was conducted for assessing spectral powers and time-domain parameters of RR variations. Postural changes from the supine to the upright position decreased the systolic blood pressure of the diabetics from 133(+/-)16 to 107(+/-)20 mmHg (p
ISSN:0386-300X