Procalcitonin as marker of infection in patients with Goodpasture's syndrome is misleading

Background. Procalcitonin (PCT) is routinely measured to differentiate autoimmune disorders from infection. There are reports, however, where PCT is high in the absence of infection, i.e. in vasculitis. To investigate the value of PCT in Goodpasture's syndrome, we reviewed the charts of patient...

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Veröffentlicht in:	Nephrology, dialysis, transplantation dialysis, transplantation, 2007-09, Vol.22 (9), p.2701-2704
Hauptverfasser:	Morath, Christian, Sis, Jeanne, Haensch, Gertrud M., Zeier, Martin, Andrassy, Konrad, Schwenger, Vedat
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anti-Glomerular Basement Membrane Disease - blood Anti-Glomerular Basement Membrane Disease - complications Anti-Glomerular Basement Membrane Disease - microbiology Biological and medical sciences Biomarkers C-Reactive Protein - metabolism Calcitonin - metabolism Calcitonin Gene-Related Peptide Communicable Diseases - complications Emergency and intensive care: renal failure. Dialysis management Female Glomerulonephritis Goodpasture's syndrome Human viral diseases Humans infection Infectious diseases inflammation Intensive care medicine Male Medical sciences Middle Aged Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure procalcitonin Protein Precursors - metabolism Time Factors Viral diseases Viral hepatitis
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Zusammenfassung:	Background. Procalcitonin (PCT) is routinely measured to differentiate autoimmune disorders from infection. There are reports, however, where PCT is high in the absence of infection, i.e. in vasculitis. To investigate the value of PCT in Goodpasture's syndrome, we reviewed the charts of patients with Goodpasture's syndrome who were treated from 1996 to 2006. Methods. PCT (normal range
ISSN:	0931-0509 1460-2385
DOI:	10.1093/ndt/gfm353