Cannabidiol - Recent Advances

The aim of this review is to present some of the recent publications on cannabidiol (CBD; 2), a major non‐psychoactive constituent of Cannabis, and to give a general overview. Special emphasis is laid on biochemical and pharmacological advances, and on novel mechanisms recently put forward, to shed...

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Veröffentlicht in:	Chemistry & biodiversity 2007-08, Vol.4 (8), p.1678-1692
Hauptverfasser:	Mechoulam, Raphael, Peters, Maximilian, Murillo-Rodriguez, Eric, Hanuš, Lumír O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - chemical synthesis Antioxidants - therapeutic use Brain Ischemia - drug therapy Cannabidiol Cannabidiol - agonists Cannabidiol - chemical synthesis Cannabidiol - therapeutic use Cannabinoid Receptor Antagonists Cannabinoids Cannabis Humans Marijuana Neoplasms - drug therapy Neuroprotective Agents - chemical synthesis Neuroprotective Agents - therapeutic use Receptor, Serotonin, 5-HT1A - drug effects Receptors, Opioid - drug effects
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Beschreibung
Zusammenfassung:	The aim of this review is to present some of the recent publications on cannabidiol (CBD; 2), a major non‐psychoactive constituent of Cannabis, and to give a general overview. Special emphasis is laid on biochemical and pharmacological advances, and on novel mechanisms recently put forward, to shed light on some of the pharmacological effects that can possibly be rationalized through these mechanisms. The plethora of positive pharmacological effects observed with CBD make this compound a highly attractive therapeutic entity.
ISSN:	1612-1872 1612-1880
DOI:	10.1002/cbdv.200790147