Multiple malignant melanomas in association with neurofibromatosis type 1
We present a case of multiple primary malignant melanomata occurring over a six year period in a 63-year-old Caucasian man with neurofibromatosis type 1. There is doubt regarding a definite association between these two diseases despite a number of case reports and clear, potential pathological mech...
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Veröffentlicht in: | Journal of plastic, reconstructive & aesthetic surgery reconstructive & aesthetic surgery, 2006-01, Vol.59 (12), p.1359-1362 |
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container_title | Journal of plastic, reconstructive & aesthetic surgery |
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creator | Barringer, C.B. Gorse, S.J. Rigby, H.S. Reid, C.D. |
description | We present a case of multiple primary malignant melanomata occurring over a six year period in a 63-year-old Caucasian man with neurofibromatosis type 1.
There is doubt regarding a definite association between these two diseases despite a number of case reports and clear, potential pathological mechanisms.
This case not only strengthens support for an association but also highlights the great difficulties that arise in the management of cutaneous melanomata in patients with neurofibromatosis. |
doi_str_mv | 10.1016/j.bjps.2006.01.024 |
format | Article |
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There is doubt regarding a definite association between these two diseases despite a number of case reports and clear, potential pathological mechanisms.
This case not only strengthens support for an association but also highlights the great difficulties that arise in the management of cutaneous melanomata in patients with neurofibromatosis.</description><identifier>ISSN: 1748-6815</identifier><identifier>EISSN: 1878-0539</identifier><identifier>DOI: 10.1016/j.bjps.2006.01.024</identifier><identifier>PMID: 17113519</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>Biological and medical sciences ; Dermatology ; Humans ; Male ; Malignant melanoma ; Medical sciences ; Melanoma - pathology ; Melanoma - surgery ; Middle Aged ; Neoplasms, Multiple Primary - pathology ; Neoplasms, Multiple Primary - surgery ; Neurofibromatosis ; Neurofibromatosis 1 - pathology ; Neurology ; Skin Neoplasms - pathology ; Skin Neoplasms - surgery ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Tumors of the nervous system. Phacomatoses ; Tumors of the skin and soft tissue. Premalignant lesions ; Von Recklinghausen's disease</subject><ispartof>Journal of plastic, reconstructive & aesthetic surgery, 2006-01, Vol.59 (12), p.1359-1362</ispartof><rights>2006 The British Association of Plastic Surgeons</rights><rights>2007 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c384t-b1b4e56c0ac822398c510d73144b5d5e19be432961e409c24a9f283ff54fb7cd3</citedby><cites>FETCH-LOGICAL-c384t-b1b4e56c0ac822398c510d73144b5d5e19be432961e409c24a9f283ff54fb7cd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1748681506001860$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18349558$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17113519$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Barringer, C.B.</creatorcontrib><creatorcontrib>Gorse, S.J.</creatorcontrib><creatorcontrib>Rigby, H.S.</creatorcontrib><creatorcontrib>Reid, C.D.</creatorcontrib><title>Multiple malignant melanomas in association with neurofibromatosis type 1</title><title>Journal of plastic, reconstructive & aesthetic surgery</title><addtitle>J Plast Reconstr Aesthet Surg</addtitle><description>We present a case of multiple primary malignant melanomata occurring over a six year period in a 63-year-old Caucasian man with neurofibromatosis type 1.
There is doubt regarding a definite association between these two diseases despite a number of case reports and clear, potential pathological mechanisms.
This case not only strengthens support for an association but also highlights the great difficulties that arise in the management of cutaneous melanomata in patients with neurofibromatosis.</description><subject>Biological and medical sciences</subject><subject>Dermatology</subject><subject>Humans</subject><subject>Male</subject><subject>Malignant melanoma</subject><subject>Medical sciences</subject><subject>Melanoma - pathology</subject><subject>Melanoma - surgery</subject><subject>Middle Aged</subject><subject>Neoplasms, Multiple Primary - pathology</subject><subject>Neoplasms, Multiple Primary - surgery</subject><subject>Neurofibromatosis</subject><subject>Neurofibromatosis 1 - pathology</subject><subject>Neurology</subject><subject>Skin Neoplasms - pathology</subject><subject>Skin Neoplasms - surgery</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Tumors of the nervous system. Phacomatoses</subject><subject>Tumors of the skin and soft tissue. Premalignant lesions</subject><subject>Von Recklinghausen's disease</subject><issn>1748-6815</issn><issn>1878-0539</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kL2O1TAQhS0EYn_gBShQGugSPLGd2BINWvGz0iIaqC3HmYCvkjh4HFb79vjqXmm7rWaK74zOfIy9Ad4Ah-7DoRkOGzUt513DoeGtfMYuQfe65kqY52Xvpa47DeqCXREdOJcCpHrJLqAHEArMJbv9vs85bDNWi5vD79WtuVpwdmtcHFVhrRxR9MHlENfqPuQ_1Yp7ilMYUiFypEBVftiwglfsxeRmwtfnec1-ffn88-Zbfffj6-3Np7vaCy1zPcAgUXWeO6_bVhjtFfCxL8XkoEaFYAaUojUdoOTGt9KZqdVimpScht6P4pq9P93dUvy7I2W7BPI4l84Yd7Ll3453yhSwPYE-RaKEk91SWFx6sMDtUaA92KNAexRoOdgisITenq_vw4LjY-RsrADvzoAj7-YpudUHeuS0kEYpXbiPJw6Li38BkyUfcPU4hoQ-2zGGp3r8B5uTjwI</recordid><startdate>20060101</startdate><enddate>20060101</enddate><creator>Barringer, C.B.</creator><creator>Gorse, S.J.</creator><creator>Rigby, H.S.</creator><creator>Reid, C.D.</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20060101</creationdate><title>Multiple malignant melanomas in association with neurofibromatosis type 1</title><author>Barringer, C.B. ; Gorse, S.J. ; Rigby, H.S. ; Reid, C.D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c384t-b1b4e56c0ac822398c510d73144b5d5e19be432961e409c24a9f283ff54fb7cd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Biological and medical sciences</topic><topic>Dermatology</topic><topic>Humans</topic><topic>Male</topic><topic>Malignant melanoma</topic><topic>Medical sciences</topic><topic>Melanoma - pathology</topic><topic>Melanoma - surgery</topic><topic>Middle Aged</topic><topic>Neoplasms, Multiple Primary - pathology</topic><topic>Neoplasms, Multiple Primary - surgery</topic><topic>Neurofibromatosis</topic><topic>Neurofibromatosis 1 - pathology</topic><topic>Neurology</topic><topic>Skin Neoplasms - pathology</topic><topic>Skin Neoplasms - surgery</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Tumors of the nervous system. Phacomatoses</topic><topic>Tumors of the skin and soft tissue. Premalignant lesions</topic><topic>Von Recklinghausen's disease</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Barringer, C.B.</creatorcontrib><creatorcontrib>Gorse, S.J.</creatorcontrib><creatorcontrib>Rigby, H.S.</creatorcontrib><creatorcontrib>Reid, C.D.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of plastic, reconstructive & aesthetic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Barringer, C.B.</au><au>Gorse, S.J.</au><au>Rigby, H.S.</au><au>Reid, C.D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Multiple malignant melanomas in association with neurofibromatosis type 1</atitle><jtitle>Journal of plastic, reconstructive & aesthetic surgery</jtitle><addtitle>J Plast Reconstr Aesthet Surg</addtitle><date>2006-01-01</date><risdate>2006</risdate><volume>59</volume><issue>12</issue><spage>1359</spage><epage>1362</epage><pages>1359-1362</pages><issn>1748-6815</issn><eissn>1878-0539</eissn><abstract>We present a case of multiple primary malignant melanomata occurring over a six year period in a 63-year-old Caucasian man with neurofibromatosis type 1.
There is doubt regarding a definite association between these two diseases despite a number of case reports and clear, potential pathological mechanisms.
This case not only strengthens support for an association but also highlights the great difficulties that arise in the management of cutaneous melanomata in patients with neurofibromatosis.</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><pmid>17113519</pmid><doi>10.1016/j.bjps.2006.01.024</doi><tpages>4</tpages></addata></record> |
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subjects | Biological and medical sciences Dermatology Humans Male Malignant melanoma Medical sciences Melanoma - pathology Melanoma - surgery Middle Aged Neoplasms, Multiple Primary - pathology Neoplasms, Multiple Primary - surgery Neurofibromatosis Neurofibromatosis 1 - pathology Neurology Skin Neoplasms - pathology Skin Neoplasms - surgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Tumors of the nervous system. Phacomatoses Tumors of the skin and soft tissue. Premalignant lesions Von Recklinghausen's disease |
title | Multiple malignant melanomas in association with neurofibromatosis type 1 |
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