Multiple malignant melanomas in association with neurofibromatosis type 1

We present a case of multiple primary malignant melanomata occurring over a six year period in a 63-year-old Caucasian man with neurofibromatosis type 1. There is doubt regarding a definite association between these two diseases despite a number of case reports and clear, potential pathological mech...

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Veröffentlicht in:Journal of plastic, reconstructive & aesthetic surgery reconstructive & aesthetic surgery, 2006-01, Vol.59 (12), p.1359-1362
Hauptverfasser: Barringer, C.B., Gorse, S.J., Rigby, H.S., Reid, C.D.
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Sprache:eng
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Zusammenfassung:We present a case of multiple primary malignant melanomata occurring over a six year period in a 63-year-old Caucasian man with neurofibromatosis type 1. There is doubt regarding a definite association between these two diseases despite a number of case reports and clear, potential pathological mechanisms. This case not only strengthens support for an association but also highlights the great difficulties that arise in the management of cutaneous melanomata in patients with neurofibromatosis.
ISSN:1748-6815
1878-0539
DOI:10.1016/j.bjps.2006.01.024