Nor-Seco-Cucurbit[10]uril Exhibits Homotropic Allosterism

Nor-Seco-Cucurbit[10]uril Exhibits Homotropic Allosterism

The condensation of glycoluril and formaldehyde in concentrated HCl at 50 °C delivers nor-seco-cucurbit[10]uril (ns-CB [10]). 1H NMR and X-ray crystallographic evidence indicates that the two cavities of ns-CB[10] accommodate guests that are typically bound within CB[6] or CB[7]. Several interesting...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of the American Chemical Society 2006-11, Vol.128 (46), p.14744-14745
Hauptverfasser: Huang, Wei-Hao, Liu, Simin, Zavalij, Peter Y, Isaacs, Lyle
Format: Artikel
Sprache:eng
Schlagworte:
Chemistry
Exact sciences and technology
General and physical chemistry
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The condensation of glycoluril and formaldehyde in concentrated HCl at 50 °C delivers nor-seco-cucurbit[10]uril (ns-CB [10]). 1H NMR and X-ray crystallographic evidence indicates that the two cavities of ns-CB[10] accommodate guests that are typically bound within CB[6] or CB[7]. Several interesting types of selectivity are possible within these ternary complexestop/center isomerism, diastereoselective complexation of chiral (but racemic) guest pairs, and guest size controlled homotropic allosterism.
ISSN:0002-7863
1520-5126
DOI:10.1021/ja064776x