Update on Kaposi's sarcoma

Kaposi's sarcoma (KS) is a mesenchymal tumor involving blood and lymphatic vessels and induced by viral growth factors (HHV8-IL6). This article reviews the epidemiology, pathogenesis, clinical spectrum (classic KS, iatrogenic immunosuppressive KS, endemic African KS, and AIDS-KS), histological...

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Veröffentlicht in:	Médecine tropicale 2007-04, Vol.67 (2), p.123-130
Hauptverfasser:	Morand, J J, Lightburn, E, Simon, F, Patte, J H
Format:	Magazinearticle
Sprache:	fre
Schlagworte:	Diagnosis, Differential Endemic Diseases Herpesvirus 8, Human - pathogenicity HIV Infections - complications Humans Immunocompromised Host Prognosis Sarcoma, Kaposi - epidemiology Sarcoma, Kaposi - pathology Sarcoma, Kaposi - therapy Sarcoma, Kaposi - virology Skin Neoplasms - epidemiology Skin Neoplasms - pathology Skin Neoplasms - therapy Skin Neoplasms - virology
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Beschreibung
Zusammenfassung:	Kaposi's sarcoma (KS) is a mesenchymal tumor involving blood and lymphatic vessels and induced by viral growth factors (HHV8-IL6). This article reviews the epidemiology, pathogenesis, clinical spectrum (classic KS, iatrogenic immunosuppressive KS, endemic African KS, and AIDS-KS), histological features, staging criteria and treatment of KS. Unlike industrialized countries that have benefited from widespread use of highly active antiretroviral therapy (HAART), developing countries continue to have a high incidence of AIDS-KS. Future therapeutic targets for KS are enhancement of immune function and treatment with angiogenesis inhibitors
ISSN:	0025-682X