The incidence of motor nueron disease in Scotland

Between 1989 and 1998, 1226 cases of ALS/MND were identified in Scotland, with mean age of onset 65.2 (SD 11.9) years for men and 67.2 (SD 11.0) for women. Annual standardized incidence was 2.40 per 100,000 (95% CI 2.22-2.58). Using capture recapture methods we confirm a high level of case ascertain...

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Veröffentlicht in:	Journal of neurology 2007-07, Vol.254 (7), p.866-869
Hauptverfasser:	FORBES, Raeburn B, COLVILLE, Shuna, PARRATT, John, SWINGLER, Robert J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age Age Factors Aged Aged, 80 and over Amyotrophic lateral sclerosis Amyotrophic Lateral Sclerosis - epidemiology Biological and medical sciences Child Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Female Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Humans Incidence Male Medical sciences Middle Aged Motor Neuron Disease - epidemiology Motor neurone disease Nervous system (semeiology, syndromes) Neurology Patients Population-based studies Reference Values Scotland - epidemiology
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Zusammenfassung:	Between 1989 and 1998, 1226 cases of ALS/MND were identified in Scotland, with mean age of onset 65.2 (SD 11.9) years for men and 67.2 (SD 11.0) for women. Annual standardized incidence was 2.40 per 100,000 (95% CI 2.22-2.58). Using capture recapture methods we confirm a high level of case ascertainment for each year of study. Incidence and ascertainment of ALS has remained stable in a large population over a prolonged period of time. Large population-based databases can be used to test aetiological hypotheses.
ISSN:	0340-5354 1432-1459
DOI:	10.1007/s00415-006-0454-y