Antimicrobial activity of aqueous extracts of Larrea divaricata Cav (jarilla) against Helicobacter pylori

We studied here the effect of aqueous extracts of Larrea divaricata Cav on the growth of Helicobacter pylori. Results show that cold extract, infusion, decoction and simulated digestion had inhibitory activity at 0.04–0.1 mg/l against clarithromycin and metronidazole susceptible and resistant H. pyl...

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Veröffentlicht in:	Phytomedicine (Stuttgart) 2006-11, Vol.13 (9), p.724-727
Hauptverfasser:	Stege, P.W., Davicino, R.C., Vega, A.E., Casali, Y.A, Correa, S., Micalizzi, B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-infective agents Antimicrobial activity Creosote bush Drug Resistance, Bacterial Health aspects Helicobacter pylori Helicobacter pylori - drug effects Larrea - chemistry Larrea divaricata Cav extracts Medicinal plants Microbial Sensitivity Tests Plant Extracts - pharmacology
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Zusammenfassung:	We studied here the effect of aqueous extracts of Larrea divaricata Cav on the growth of Helicobacter pylori. Results show that cold extract, infusion, decoction and simulated digestion had inhibitory activity at 0.04–0.1 mg/l against clarithromycin and metronidazole susceptible and resistant H. pylori strains. These results support the popular use of L. divaricata Cav in gastric disturbances and prompt further research to characterize these compounds with a therapeutic potential against gastric ulcers and gastric cancer associated with H. pylori.
ISSN:	0944-7113 1618-095X
DOI:	10.1016/j.phymed.2005.06.008