Synthesis and Incorporation of a Cationic Pyridinium Nucleoside Mimic in Duplex DNA:  Effect on Long-Distance Radical Cation Transport

Synthesis and Incorporation of a Cationic Pyridinium Nucleoside Mimic in Duplex DNA:  Effect on Long-Distance Radical Cation Transport

A convenient method for the synthesis and solid-phase incorporation of a cationic nucleoside mimic and its role in DNA long-range charge transfer are described.

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Veröffentlicht in:Organic letters 2006-11, Vol.8 (23), p.5255-5258
Hauptverfasser: Onyemauwa, Frank O, Schuster, Gary B
Format: Artikel
Sprache:eng
Schlagworte:
Cations - chemistry
DNA - chemistry
DNA Methylation
Molecular Mimicry
Pyridinium Compounds - chemical synthesis
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Beschreibung
Zusammenfassung:A convenient method for the synthesis and solid-phase incorporation of a cationic nucleoside mimic and its role in DNA long-range charge transfer are described.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol062075z