Candida pseudohaemulonii Sp. Nov., an Amphotericin B- and Azole-Resistant Yeast Species, Isolated from the Blood of a Patient from Thailand

Candida haemulonii (types I and II) is rarely isolated from clinical specimens. We isolated a strain that is phylogenetically close to C. haemulonii from the blood of a Thai patient, and named it C. pseudohaemulonii sp. nov. (CBS 10099T=JCM 12453T=DMST 17134T). The new species and C. haemulonii type...

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Veröffentlicht in:	Microbiology and immunology 2006-01, Vol.50 (6), p.469-473
Hauptverfasser:	Sugita, Takashi, Takashima, Masako, Poonwan, Natteewan, Mekha, Nanthawan
Format:	Artikel
Sprache:	eng
Schlagworte:	amphotericin B Amphotericin B - pharmacology Antifungal Agents - pharmacology azole Candida - classification Candida - drug effects Candida - isolation & purification candida haemulonii Candida pseudohaemulonii Drug Resistance, Fungal Fluconazole - pharmacology Fungemia - microbiology Microbial Sensitivity Tests new species Phylogeny
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Zusammenfassung:	Candida haemulonii (types I and II) is rarely isolated from clinical specimens. We isolated a strain that is phylogenetically close to C. haemulonii from the blood of a Thai patient, and named it C. pseudohaemulonii sp. nov. (CBS 10099T=JCM 12453T=DMST 17134T). The new species and C. haemulonii types I and II were resistant to amphotericin B and azole agents but were susceptible to a 1,3‐β‐D‐glucan synthetase inhibitor, micafungin, and 5‐flucytosine. The species were easily distinguished using an ID32 yeast identification kit. The taxonomic description of C. pseudohaemulonii sp. nov. is presented.
ISSN:	0385-5600 1348-0421
DOI:	10.1111/j.1348-0421.2006.tb03816.x