The role of the cellular immunity in the process of the operative wound healing

Phagocyte ability of the cells of connective tissue has an essential role in the development of the immune response. The Kavetski test has been applied on 199 patients with different types of the laparotomy wounds (average age - 14-74 years) in order to detect the intensity of the phagocytosis. Based on the peculiarity of the wound process flow, two groups of the patients have been distinguished. The first group (132 patients) included the patients with primary intention of laparotomy wounds; while the second group included 67 patients with complicated dynamics of the wound process (healing by secondary intention, total or partial suppuration, inflammatory infiltrate, ligature fistulas, serous hemorrhagic effusion from the wound). The percentage of the above mentioned groups by the principal disease, volume and type of the surgical intervention, type of the anesthesia, age, follow-up time and method of treatment were about the equal. Our study showed that the phagocytic intensity positively correlated with the laparotomy wound healing: higher level of the phagocytosis was associated with the less number of the frequency of complications of wound healing.