JBMR anniversary classic. Nitrogen-containing biophosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras. Originally published in Volume 7, number 4, pp 581-9 (1998)

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of bone and mineral research 2005-07, Vol.20 (7), p.1265-1274
Hauptverfasser:	Luckman, Steven P, Hughes, David E, Coxon, Fraser P, Russell, Graham G, Rogers, Michael J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone Resorption - history Bone Resorption - metabolism Cells, Cultured Diphosphonates - history Diphosphonates - pharmacology GTP-Binding Proteins - history GTP-Binding Proteins - metabolism History, 20th Century Lovastatin - analogs & derivatives Lovastatin - history Lovastatin - pharmacology Mevalonic Acid - history Mevalonic Acid - metabolism Mice Osteoclasts - drug effects Osteoclasts - metabolism Protein Prenylation - drug effects ras Proteins - history ras Proteins - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!