Hypertrophic Lupus Erythematosus Treated Successfully with Acitretin as Monotherapy

Hypertrophic Lupus Erythematosus Treated Successfully with Acitretin as Monotherapy

Hypertrophic lupus erythematosus (HLE) is a distinct and rare subset of chronic cutaneous lupus erythematosus characterized by verrucous lesions which are chronic in course and resistant to treatment (1). We describe the successful use of acitretin in a patient with HLE who had multiple hyperkeratot...

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Veröffentlicht in:Journal of dermatology 2005-06, Vol.32 (6), p.482-486
Hauptverfasser: Al‐Mutairi, Nawaf, Rijhwani, Manish, Nour‐Eldin, Osama
Format: Artikel
Sprache:eng
Schlagworte:
acitretin
Acitretin - therapeutic use
Adult
Biopsy, Needle
Dose-Response Relationship, Drug
Drug Administration Schedule
Follow-Up Studies
Humans
hypertrophic lupus erythematosus
Hypertrophy - drug therapy
Hypertrophy - pathology
Immunohistochemistry
Keratolytic Agents - therapeutic use
Lupus Erythematosus, Discoid - drug therapy
Lupus Erythematosus, Discoid - pathology
Male
Severity of Illness Index
Treatment Outcome
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Zusammenfassung:Hypertrophic lupus erythematosus (HLE) is a distinct and rare subset of chronic cutaneous lupus erythematosus characterized by verrucous lesions which are chronic in course and resistant to treatment (1). We describe the successful use of acitretin in a patient with HLE who had multiple hyperkeratotic verrucous plaques over the dorsa of his hands, feet, and legs and who failed to respond to local steroids and antimalarials.
ISSN:0385-2407
1346-8138
DOI:10.1111/j.1346-8138.2005.tb00785.x