Limnophilaspiroketone, a highly oxygenated phenolic derivative from Limnophila geoffrayi

A highly oxygenated phenolic spiroketone, limnophilaspiroketone (1), was isolated from the aerial parts of Limnophila geoffrayi collected in Thailand. The structure of 1 was determined based on spectroscopic data interpretation. This novel isolate, obtained as a major secondary metabolite constituen...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2005-07, Vol.68 (7), p.1134-1136
Hauptverfasser:	Jang, D.S, Su, B.N, Pawlus, A.D, Jones, W.P, Kleps, R.A, Bunyapraphatsara, N, Fong, H.H.S, Pezzuto, J.M, Kinghorn, A.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences chemical structure General pharmacology Limnophila Limnophila geoffrayi limnophilaspiroketone Medical sciences medicinal plants Mice Molecular Structure Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments phenolic compounds Phenols - chemistry Phenols - isolation & purification phytochemicals Plants, Medicinal - chemistry Scrophulariaceae - chemistry spectral analysis stereochemistry Thailand traditional medicine Tumor Cells, Cultured vegetable crops
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Beschreibung
Zusammenfassung:	A highly oxygenated phenolic spiroketone, limnophilaspiroketone (1), was isolated from the aerial parts of Limnophila geoffrayi collected in Thailand. The structure of 1 was determined based on spectroscopic data interpretation. This novel isolate, obtained as a major secondary metabolite constituent, was verified as a racemate using the Mosher ester method.
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np050132b