Antimicrobial Activity of Isopteropodine

Bioassay-directed fractionation for the determination of antimicrobial activity of Uncaria tomentosa, has led to the isolation of isopteropodine (0.3%), a known Uncaria pentacyclic oxindol alkaloid that exhibited antibacterial activity against Gram positive bacteria.

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Veröffentlicht in:	Zeitschrift für Naturforschung C. A journal of biosciences 2005-06, Vol.60 (5), p.385-388
Hauptverfasser:	García, Rubén, Cayunao, Cesia, Bocic, Ronny, Backhouse, Nadine, Delporte, Carla, Zaldivar, Mercedes, Erazo, Silvia
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Infective Agents - chemistry Anti-Infective Agents - isolation & purification Antibacterial Activity Bacteria - drug effects Gas Chromatography-Mass Spectrometry Isopteropodine Magnetic Resonance Spectroscopy Microbial Sensitivity Tests Phytotherapy Plant Extracts Plant Stems - chemistry Saccharomyces cerevisiae - drug effects Uncaria - chemistry Uncaria tomentosa
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Beschreibung
Zusammenfassung:	Bioassay-directed fractionation for the determination of antimicrobial activity of Uncaria tomentosa, has led to the isolation of isopteropodine (0.3%), a known Uncaria pentacyclic oxindol alkaloid that exhibited antibacterial activity against Gram positive bacteria.
ISSN:	0939-5075 1865-7125
DOI:	10.1515/znc-2005-5-603