A new approach to phospholipid synthesis using tetrahydropyranyl glycerol: rapid access to phosphatidic acid and phosphatidylcholine, including mixed-chain glycerophospholipid derivatives

A new approach to phospholipid synthesis using tetrahydropyranyl glycerol: rapid access to phosphatidic acid and phosphatidylcholine, including mixed-chain glycerophospholipid derivatives

A new synthesis of phosphatidic acid and phosphatidylcholine is reported, relying on the preparation of 3-tetrahydropyranyl-sn-glycerol as the key intermediate for sequential introduction of the primary and secondary acyl functions to produce chiral diglycerides that are phosphorylated to obtain the...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Organic & biomolecular chemistry 2006-01, Vol.4 (12), p.2358-2360
Hauptverfasser: Rosseto, Renato, Bibak, Niloufar, Hajdu, Joseph
Format: Artikel
Sprache:eng
Schlagworte:
Glycerol - analogs & derivatives
Glycerol - chemistry
Glycerophospholipids - chemical synthesis
Phosphatidic Acids - chemical synthesis
Phosphatidylcholines - chemical synthesis
Phospholipids - chemical synthesis
Phosphorylation
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 2360
container_issue 12
container_start_page 2358
container_title Organic & biomolecular chemistry
container_volume 4
creator Rosseto, Renato
Bibak, Niloufar
Hajdu, Joseph
description A new synthesis of phosphatidic acid and phosphatidylcholine is reported, relying on the preparation of 3-tetrahydropyranyl-sn-glycerol as the key intermediate for sequential introduction of the primary and secondary acyl functions to produce chiral diglycerides that are phosphorylated to obtain the target phospholipid compounds.
doi_str_mv 10.1039/b603788g
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68058105</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>68058105</sourcerecordid><originalsourceid>FETCH-LOGICAL-c301t-c91ac90c5cac5e0b9c4f97c4a7cb1d87845b9eb121f49583f6143762e038a093</originalsourceid><addsrcrecordid>eNpVUctu3DAMFIoGzWZboF8Q6FT0ECfSyras3BaLvIAAueRuyBS9VqGVHcne1t_Wn4uNbF4HggQ5nCE4hPzk7JwzoS6qnAlZFNsvZMFTKROWCfX1rV6xY3IS4x_GuJJ5-o0c81zmIpdqQf6vqce_VHddaDU0tG9p17RxCmc7a2gcfd9gtJEO0fot7bEPuhlNaLsxaD86unUjYGjdJQ163tAAGOM7ke6tsTC155k3H7qjg1nG4xm1HtxgZoGd_YcmgUZb_0r96SCDwe6n7T3G7-So1i7ij0Neksfrq8fNbXL_cHO3Wd8nIBjvE1Bcg2KQgYYMWaUgrZWEVEuouClkkWaVwoqveJ2qrBB1zlMh8xUyUWimxJL8eqGdXvQ0YOzLnY2AzmmP7RDLvGBZwaeXL8nvFyCENsaAddkFu9NhLDkrZ5_KV58m6OmBc6h2aN6BB2PEM6ozlGo</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>68058105</pqid></control><display><type>article</type><title>A new approach to phospholipid synthesis using tetrahydropyranyl glycerol: rapid access to phosphatidic acid and phosphatidylcholine, including mixed-chain glycerophospholipid derivatives</title><source>MEDLINE</source><source>Royal Society of Chemistry Journals Archive (1841-2007)</source><source>Royal Society Of Chemistry Journals 2008-</source><source>Alma/SFX Local Collection</source><creator>Rosseto, Renato ; Bibak, Niloufar ; Hajdu, Joseph</creator><creatorcontrib>Rosseto, Renato ; Bibak, Niloufar ; Hajdu, Joseph</creatorcontrib><description>A new synthesis of phosphatidic acid and phosphatidylcholine is reported, relying on the preparation of 3-tetrahydropyranyl-sn-glycerol as the key intermediate for sequential introduction of the primary and secondary acyl functions to produce chiral diglycerides that are phosphorylated to obtain the target phospholipid compounds.</description><identifier>ISSN: 1477-0520</identifier><identifier>EISSN: 1477-0539</identifier><identifier>DOI: 10.1039/b603788g</identifier><identifier>PMID: 16763679</identifier><language>eng</language><publisher>England</publisher><subject>Glycerol - analogs &amp; derivatives ; Glycerol - chemistry ; Glycerophospholipids - chemical synthesis ; Phosphatidic Acids - chemical synthesis ; Phosphatidylcholines - chemical synthesis ; Phospholipids - chemical synthesis ; Phosphorylation</subject><ispartof>Organic &amp; biomolecular chemistry, 2006-01, Vol.4 (12), p.2358-2360</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c301t-c91ac90c5cac5e0b9c4f97c4a7cb1d87845b9eb121f49583f6143762e038a093</citedby><cites>FETCH-LOGICAL-c301t-c91ac90c5cac5e0b9c4f97c4a7cb1d87845b9eb121f49583f6143762e038a093</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,2831,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16763679$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rosseto, Renato</creatorcontrib><creatorcontrib>Bibak, Niloufar</creatorcontrib><creatorcontrib>Hajdu, Joseph</creatorcontrib><title>A new approach to phospholipid synthesis using tetrahydropyranyl glycerol: rapid access to phosphatidic acid and phosphatidylcholine, including mixed-chain glycerophospholipid derivatives</title><title>Organic &amp; biomolecular chemistry</title><addtitle>Org Biomol Chem</addtitle><description>A new synthesis of phosphatidic acid and phosphatidylcholine is reported, relying on the preparation of 3-tetrahydropyranyl-sn-glycerol as the key intermediate for sequential introduction of the primary and secondary acyl functions to produce chiral diglycerides that are phosphorylated to obtain the target phospholipid compounds.</description><subject>Glycerol - analogs &amp; derivatives</subject><subject>Glycerol - chemistry</subject><subject>Glycerophospholipids - chemical synthesis</subject><subject>Phosphatidic Acids - chemical synthesis</subject><subject>Phosphatidylcholines - chemical synthesis</subject><subject>Phospholipids - chemical synthesis</subject><subject>Phosphorylation</subject><issn>1477-0520</issn><issn>1477-0539</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVUctu3DAMFIoGzWZboF8Q6FT0ECfSyras3BaLvIAAueRuyBS9VqGVHcne1t_Wn4uNbF4HggQ5nCE4hPzk7JwzoS6qnAlZFNsvZMFTKROWCfX1rV6xY3IS4x_GuJJ5-o0c81zmIpdqQf6vqce_VHddaDU0tG9p17RxCmc7a2gcfd9gtJEO0fot7bEPuhlNaLsxaD86unUjYGjdJQ163tAAGOM7ke6tsTC155k3H7qjg1nG4xm1HtxgZoGd_YcmgUZb_0r96SCDwe6n7T3G7-So1i7ij0Neksfrq8fNbXL_cHO3Wd8nIBjvE1Bcg2KQgYYMWaUgrZWEVEuouClkkWaVwoqveJ2qrBB1zlMh8xUyUWimxJL8eqGdXvQ0YOzLnY2AzmmP7RDLvGBZwaeXL8nvFyCENsaAddkFu9NhLDkrZ5_KV58m6OmBc6h2aN6BB2PEM6ozlGo</recordid><startdate>20060101</startdate><enddate>20060101</enddate><creator>Rosseto, Renato</creator><creator>Bibak, Niloufar</creator><creator>Hajdu, Joseph</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20060101</creationdate><title>A new approach to phospholipid synthesis using tetrahydropyranyl glycerol: rapid access to phosphatidic acid and phosphatidylcholine, including mixed-chain glycerophospholipid derivatives</title><author>Rosseto, Renato ; Bibak, Niloufar ; Hajdu, Joseph</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c301t-c91ac90c5cac5e0b9c4f97c4a7cb1d87845b9eb121f49583f6143762e038a093</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Glycerol - analogs &amp; derivatives</topic><topic>Glycerol - chemistry</topic><topic>Glycerophospholipids - chemical synthesis</topic><topic>Phosphatidic Acids - chemical synthesis</topic><topic>Phosphatidylcholines - chemical synthesis</topic><topic>Phospholipids - chemical synthesis</topic><topic>Phosphorylation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rosseto, Renato</creatorcontrib><creatorcontrib>Bibak, Niloufar</creatorcontrib><creatorcontrib>Hajdu, Joseph</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Organic &amp; biomolecular chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rosseto, Renato</au><au>Bibak, Niloufar</au><au>Hajdu, Joseph</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A new approach to phospholipid synthesis using tetrahydropyranyl glycerol: rapid access to phosphatidic acid and phosphatidylcholine, including mixed-chain glycerophospholipid derivatives</atitle><jtitle>Organic &amp; biomolecular chemistry</jtitle><addtitle>Org Biomol Chem</addtitle><date>2006-01-01</date><risdate>2006</risdate><volume>4</volume><issue>12</issue><spage>2358</spage><epage>2360</epage><pages>2358-2360</pages><issn>1477-0520</issn><eissn>1477-0539</eissn><abstract>A new synthesis of phosphatidic acid and phosphatidylcholine is reported, relying on the preparation of 3-tetrahydropyranyl-sn-glycerol as the key intermediate for sequential introduction of the primary and secondary acyl functions to produce chiral diglycerides that are phosphorylated to obtain the target phospholipid compounds.</abstract><cop>England</cop><pmid>16763679</pmid><doi>10.1039/b603788g</doi><tpages>3</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1477-0520
ispartof Organic & biomolecular chemistry, 2006-01, Vol.4 (12), p.2358-2360
issn 1477-0520
1477-0539
language eng
recordid cdi_proquest_miscellaneous_68058105
source MEDLINE; Royal Society of Chemistry Journals Archive (1841-2007); Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
subjects Glycerol - analogs & derivatives
Glycerol - chemistry
Glycerophospholipids - chemical synthesis
Phosphatidic Acids - chemical synthesis
Phosphatidylcholines - chemical synthesis
Phospholipids - chemical synthesis
Phosphorylation
title A new approach to phospholipid synthesis using tetrahydropyranyl glycerol: rapid access to phosphatidic acid and phosphatidylcholine, including mixed-chain glycerophospholipid derivatives
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-30T23%3A38%3A07IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20new%20approach%20to%20phospholipid%20synthesis%20using%20tetrahydropyranyl%20glycerol:%20rapid%20access%20to%20phosphatidic%20acid%20and%20phosphatidylcholine,%20including%20mixed-chain%20glycerophospholipid%20derivatives&rft.jtitle=Organic%20&%20biomolecular%20chemistry&rft.au=Rosseto,%20Renato&rft.date=2006-01-01&rft.volume=4&rft.issue=12&rft.spage=2358&rft.epage=2360&rft.pages=2358-2360&rft.issn=1477-0520&rft.eissn=1477-0539&rft_id=info:doi/10.1039/b603788g&rft_dat=%3Cproquest_cross%3E68058105%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=68058105&rft_id=info:pmid/16763679&rfr_iscdi=true