Effects of bradysole and dibasole on cerebral bloodflow under experimental conditions

Bradysole (1 mg/kg intravenously) induced a moderate increase in cerebral bloodflow and a minor decrease in systemic blood pressure in narcotized rats. These effects were less pronounced compared to the effects of dibasole (bradysole structural analog) in the same dose.

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Veröffentlicht in:Bulletin of experimental biology and medicine 2005-03, Vol.139 (3), p.322-323
Hauptverfasser: Galenko-Yaroshevskii, P A, Turovaya, A Yu, Uvarov, A V, Ivashev, M N, Arl't, A V
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container_issue 3
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container_title Bulletin of experimental biology and medicine
container_volume 139
creator Galenko-Yaroshevskii, P A
Turovaya, A Yu
Uvarov, A V
Ivashev, M N
Arl't, A V
description Bradysole (1 mg/kg intravenously) induced a moderate increase in cerebral bloodflow and a minor decrease in systemic blood pressure in narcotized rats. These effects were less pronounced compared to the effects of dibasole (bradysole structural analog) in the same dose.
doi_str_mv 10.1007/s10517-005-0283-5
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subjects Animals
Benzimidazoles - pharmacology
Blood Pressure - drug effects
Blood Pressure - physiology
Cerebrovascular Circulation - drug effects
Cerebrovascular Circulation - physiology
Dose-Response Relationship, Drug
Male
Neurotransmitter Agents - chemistry
Neurotransmitter Agents - pharmacology
Rats
Rats, Wistar
Sulfhydryl Compounds - pharmacology
Time Factors
title Effects of bradysole and dibasole on cerebral bloodflow under experimental conditions
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