Epileptiform EEG abnormalities in children with language regression

The authors examined the records of 149 children with language regression (LR) who had overnight EEG monitoring. Children with isolated LR had a higher frequency of epileptiform abnormalities (60%) than those with LR in the context of autistic regression (31%, p = 0.002) and also a higher rate of cl...

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Veröffentlicht in:	Neurology 2005-07, Vol.65 (1), p.129-131
Hauptverfasser:	MCVICAR, K. A, BALLABAN-GIL, K, RAPIN, I, MOSHE, S. L, SHINNAR, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - physiology Age of Onset Autistic Disorder - complications Autistic Disorder - diagnosis Autistic Disorder - physiopathology Biological and medical sciences Cerebral Cortex - physiopathology Child, Preschool Disease Progression Electrodiagnosis. Electric activity recording Electroencephalography Epilepsy - complications Epilepsy - diagnosis Epilepsy - physiopathology Female Humans Investigative techniques, diagnostic techniques (general aspects) Language Development Disorders - diagnosis Language Development Disorders - etiology Language Development Disorders - physiopathology Male Medical sciences Monitoring, Physiologic Nervous system Nervous system (semeiology, syndromes) Nervous system as a whole Neurology Polysomnography Predictive Value of Tests Prognosis Regression (Psychology) Retrospective Studies Sex Factors
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Zusammenfassung:	The authors examined the records of 149 children with language regression (LR) who had overnight EEG monitoring. Children with isolated LR had a higher frequency of epileptiform abnormalities (60%) than those with LR in the context of autistic regression (31%, p = 0.002) and also a higher rate of clinical seizures (33% vs 8%, p < 0.001). EEG abnormalities in the LR only group were also more prominent. This suggests two subtypes of language regression.
ISSN:	0028-3878 1526-632X
DOI:	10.1212/01.wnl.0000167193.53817.0f