Lipoatrophic men 44 months after the diagnosis of lipoatrophy are less lipoatrophic but more hypertensive
Objectives To identify clinical factors associated with HIV‐associated lipoatrophy and to evaluate body composition changes, blood pressure and lipid levels in lipoatrophic subjects 3–4 years after the atrophy diagnosis. Methods Clinical signs of lipoatrophy were assessed in 308 ambulant HIV‐positiv...
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Veröffentlicht in: | HIV medicine 2005-07, Vol.6 (4), p.260-267 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Objectives
To identify clinical factors associated with HIV‐associated lipoatrophy and to evaluate body composition changes, blood pressure and lipid levels in lipoatrophic subjects 3–4 years after the atrophy diagnosis.
Methods
Clinical signs of lipoatrophy were assessed in 308 ambulant HIV‐positive patients in 2000–2001. Possible clinical risk factors, such as age, gender, race, wasting, duration of HIV infection, presence or absence of AIDS diagnosis, viral load and CD4 count, and detailed information about drug treatment were analysed and explored in a multivariate model. Lipoatrophic white males with triceps skin fold 7 kg compared to normal weight [odds ratio (OR) 3.76; 95% confidence interval (CI) 1.80–7.82; P80 months (OR 2.28; 95% CI 1.13–4.59; P=0.021). Forty of 47 lipoatrophic white males with skin fold |
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ISSN: | 1464-2662 1468-1293 |
DOI: | 10.1111/j.1468-1293.2005.00305.x |