Is asthma research in dead end?

Despite enormous therapeutic advances, bronchial asthma remains a highly prevalent and serious health problem. Although we have learnt much about the pathogenesis of asthma and developed some new drugs within the last few years, there is still an urgent need for new treatments. The so-called single...

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Veröffentlicht in:Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 2006-06, Vol.57, p.45-47
Hauptverfasser: Amon, Annette, Pahl, Andreas, Szelenyi, Istvan
Format: Artikel
Sprache:eng
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Zusammenfassung:Despite enormous therapeutic advances, bronchial asthma remains a highly prevalent and serious health problem. Although we have learnt much about the pathogenesis of asthma and developed some new drugs within the last few years, there is still an urgent need for new treatments. The so-called single mediator approach appears to be ineffective in the treatment of asthma. Drugs with multiple sites of mode of action would have greater chances to be successfully introduced into therapy. The present drug screening strategy should be reconsidered and probably be replaced by new and more serendipity-based research.
ISSN:0940-2993
1618-1433
DOI:10.1016/j.etp.2006.02.006