Axillary lymph node count is lower after neoadjuvant chemotherapy

Retrieval of fewer than 10 lymph nodes at axillary dissection (ALND) for breast cancer can represent anatomic variation or inadequate dissection. We postulated that despite aggressive ALND, a lower lymph node count is more frequent after neoadjuvant chemotherapy. Patients who received neoadjuvant ch...

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Veröffentlicht in:	The American journal of surgery 2006-06, Vol.191 (6), p.827-829
Hauptverfasser:	Neuman, Heather, Carey, Lisa A., Ollila, David W., Livasy, Chad, Calvo, Benjamin F., Meyer, Anthony A., Kim, Hong Jin, Meyers, Michael O., Dees, E. Claire, Collichio, Fran A., Sartor, Carolyn I., Moore, Dominic T., Sawyer, Lynda R., Frank, Jill, Klauber-DeMore, Nancy
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Aged Aged, 80 and over Antineoplastic Agents - therapeutic use Axilla Axillary lymph node dissection Biopsy Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - pathology Breast Neoplasms - surgery Cancer surgery Cancer therapies Chemotherapy Dissection Female Humans Locally advanced breast cancer Lymph Node Excision - methods Lymph node retrieval Lymph Nodes - pathology Lymph Nodes - surgery Lymphatic Metastasis - pathology Lymphatic Metastasis - prevention & control Lymphatic system Mastectomy - methods Mathematical models Middle Aged Neoadjuvant Therapy Neoplasm Invasiveness - pathology Neoplasm Staging Pathology Patients Probability Prognosis Prospective Studies Sentinel Lymph Node Biopsy Statistics, Nonparametric Surgery Surgical techniques Teaching hospitals Treatment Outcome
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Zusammenfassung:	Retrieval of fewer than 10 lymph nodes at axillary dissection (ALND) for breast cancer can represent anatomic variation or inadequate dissection. We postulated that despite aggressive ALND, a lower lymph node count is more frequent after neoadjuvant chemotherapy. Patients who received neoadjuvant chemotherapy followed by ALND were compared with patients who received surgery first. All patients received a level I and II ALND at a single institution by one of the breast surgeons. The number of nodes retrieved at ALND was dichotomized into categories (
ISSN:	0002-9610 1879-1883
DOI:	10.1016/j.amjsurg.2005.08.041