Retinal vascular integrity following correction of diabetic ketoacidosis in children and adolescents

Increased permeability of the cerebral microvasculature occurs during the treatment of diabetic ketoacidosis (DKA). Microvascular changes consistent with diabetic retinopathy have been reported prior to and after the treatment of DKA. This study evaluated the structural and functional aspects of the...

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Veröffentlicht in:	Journal of diabetes and its complications 2005-07, Vol.19 (4), p.233-237
Hauptverfasser:	Martin, S. Lee Anne, Hoffman, William H., Marcus, Dennis M., Passmore, Gregory G., Dalton, Rory R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Blood-Retinal Barrier Child Children & youth Diabetes Diabetic ketoacidosis Diabetic Ketoacidosis - complications Diabetic Ketoacidosis - metabolism Diabetic retinopathy Diabetic Retinopathy - physiopathology Female Humans Hyperglycemia Hypertension Male Medical imaging Pediatrics Permeability Proteins Retinal imaging Teenagers Vascular endothelial growth factor
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Zusammenfassung:	Increased permeability of the cerebral microvasculature occurs during the treatment of diabetic ketoacidosis (DKA). Microvascular changes consistent with diabetic retinopathy have been reported prior to and after the treatment of DKA. This study evaluated the structural and functional aspects of the retina immediately following the correction of DKA. Seven young patients had comprehensive ophthalmologic examinations, including fluorescein angiography, within 24 h after the correction of severe DKA (pH
ISSN:	1056-8727 1873-460X
DOI:	10.1016/j.jdiacomp.2004.08.005