Four new HLA class I alleles in Cauacasoids
: Four new HLA classical class I alleles in the three loci are described in Caucasian individuals. A*3012 was first suspected by an abnormal serologic pattern that would be explained by the single amino acid substitution at the A30‐specific Ser17. B*270505 differs from B*270502 in a silent substitu...
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| Veröffentlicht in: | Tissue antigens 2005-07, Vol.66 (1), p.51-53 |
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| container_title | Tissue antigens |
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| creator | Alonso-Nieto, M. García-Sánchez, F. Lillo, R. Balas, A. Blanco, L. Aviles-Egea, M.J. Zarapuz, L. Vicario, J.L. |
| description | : Four new HLA classical class I alleles in the three loci are described in Caucasian individuals. A*3012 was first suspected by an abnormal serologic pattern that would be explained by the single amino acid substitution at the A30‐specific Ser17. B*270505 differs from B*270502 in a silent substitution at an up to now constant position in the B locus. B*3541 encodes for a new Cys at position 118 that has not been encountered in neither human nor primate alleles. Cw*0716 seems to be originated by a large‐scale interallelic recombination event between Cw*0701/*0706/*0718 and Cw*020202, giving rise to a new antigen‐binding cleft conformation. |
| doi_str_mv | 10.1111/j.1399-0039.2005.00421.x |
| format | Article |
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A*3012 was first suspected by an abnormal serologic pattern that would be explained by the single amino acid substitution at the A30‐specific Ser17. B*270505 differs from B*270502 in a silent substitution at an up to now constant position in the B locus. B*3541 encodes for a new Cys at position 118 that has not been encountered in neither human nor primate alleles. Cw*0716 seems to be originated by a large‐scale interallelic recombination event between Cw*0701/*0706/*0718 and Cw*020202, giving rise to a new antigen‐binding cleft conformation.</description><identifier>ISSN: 0001-2815</identifier><identifier>EISSN: 1399-0039</identifier><identifier>DOI: 10.1111/j.1399-0039.2005.00421.x</identifier><identifier>PMID: 15982258</identifier><language>eng</language><publisher>Oxford, UK; Malden, USA: Munksgaard International Publishers</publisher><subject>A3012 ; Alleles ; Amino Acid Sequence ; B270505 ; B3541 ; Base Sequence ; Cw0716 ; Cysteine - genetics ; European Continental Ancestry Group ; Genes, MHC Class I - genetics ; Heterozygote ; Histocompatibility Antigens Class I - genetics ; Histocompatibility Testing ; HLA-A Antigens - genetics ; HLA-B Antigens - genetics ; HLA-C Antigens - genetics ; Humans ; Introns ; Molecular Sequence Data ; Mutation ; new HLA class I alleles ; Polymorphism, Genetic ; Recombination, Genetic</subject><ispartof>Tissue antigens, 2005-07, Vol.66 (1), p.51-53</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4351-206a85874808127e5460af9b51402cd1212b4062f7ff2761007b3c2d70e845453</citedby><cites>FETCH-LOGICAL-c4351-206a85874808127e5460af9b51402cd1212b4062f7ff2761007b3c2d70e845453</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1399-0039.2005.00421.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1399-0039.2005.00421.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15982258$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Alonso-Nieto, M.</creatorcontrib><creatorcontrib>García-Sánchez, F.</creatorcontrib><creatorcontrib>Lillo, R.</creatorcontrib><creatorcontrib>Balas, A.</creatorcontrib><creatorcontrib>Blanco, L.</creatorcontrib><creatorcontrib>Aviles-Egea, M.J.</creatorcontrib><creatorcontrib>Zarapuz, L.</creatorcontrib><creatorcontrib>Vicario, J.L.</creatorcontrib><title>Four new HLA class I alleles in Cauacasoids</title><title>Tissue antigens</title><addtitle>Tissue Antigens</addtitle><description>: Four new HLA classical class I alleles in the three loci are described in Caucasian individuals. A*3012 was first suspected by an abnormal serologic pattern that would be explained by the single amino acid substitution at the A30‐specific Ser17. B*270505 differs from B*270502 in a silent substitution at an up to now constant position in the B locus. B*3541 encodes for a new Cys at position 118 that has not been encountered in neither human nor primate alleles. Cw*0716 seems to be originated by a large‐scale interallelic recombination event between Cw*0701/*0706/*0718 and Cw*020202, giving rise to a new antigen‐binding cleft conformation.</description><subject>A3012</subject><subject>Alleles</subject><subject>Amino Acid Sequence</subject><subject>B270505</subject><subject>B3541</subject><subject>Base Sequence</subject><subject>Cw0716</subject><subject>Cysteine - genetics</subject><subject>European Continental Ancestry Group</subject><subject>Genes, MHC Class I - genetics</subject><subject>Heterozygote</subject><subject>Histocompatibility Antigens Class I - genetics</subject><subject>Histocompatibility Testing</subject><subject>HLA-A Antigens - genetics</subject><subject>HLA-B Antigens - genetics</subject><subject>HLA-C Antigens - genetics</subject><subject>Humans</subject><subject>Introns</subject><subject>Molecular Sequence Data</subject><subject>Mutation</subject><subject>new HLA class I alleles</subject><subject>Polymorphism, Genetic</subject><subject>Recombination, Genetic</subject><issn>0001-2815</issn><issn>1399-0039</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkF1PwjAUhhujEfz4C2ZX3pjN065d28QbQhyQIEaD4bLpti4ZDoYrC_Dv7RzBS-1Ne9LnPSfnQcjDEGB3HpcBDqX0AUIZEAAWAFCCg_0Z6p8-zlEfALBPBGY9dGXt0lWUS3mJephJQQgTffQQV03trc3OG08HXlpqa72Jp8vSlMZ6xdob6kan2lZFZm_QRa5La26P9zX6iJ_nw7E_fR1NhoOpn9KQuYEQacEEpwIEJtwwGoHOZcIwBZJmmGCSUIhIzvOc8AgD8CRMScbBCMooC6_Rfdd3U1dfjbFbtSpsaspSr03VWBVxyYUk8CeIOQjCWORA0YFpXVlbm1xt6mKl64PCoFqjaqlacaoVp1qj6seo2rvo3XFGk6xM9hs8KnTAUwfsitIc_t1YzQcz93Bxv4sXdmv2p7iuP92eIWdqMRupF754H8UkVm_hN4Rijqc</recordid><startdate>200507</startdate><enddate>200507</enddate><creator>Alonso-Nieto, M.</creator><creator>García-Sánchez, F.</creator><creator>Lillo, R.</creator><creator>Balas, A.</creator><creator>Blanco, L.</creator><creator>Aviles-Egea, M.J.</creator><creator>Zarapuz, L.</creator><creator>Vicario, J.L.</creator><general>Munksgaard International Publishers</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>200507</creationdate><title>Four new HLA class I alleles in Cauacasoids</title><author>Alonso-Nieto, M. ; García-Sánchez, F. ; Lillo, R. ; Balas, A. ; Blanco, L. ; Aviles-Egea, M.J. ; Zarapuz, L. ; Vicario, J.L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4351-206a85874808127e5460af9b51402cd1212b4062f7ff2761007b3c2d70e845453</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>A3012</topic><topic>Alleles</topic><topic>Amino Acid Sequence</topic><topic>B270505</topic><topic>B3541</topic><topic>Base Sequence</topic><topic>Cw0716</topic><topic>Cysteine - genetics</topic><topic>European Continental Ancestry Group</topic><topic>Genes, MHC Class I - genetics</topic><topic>Heterozygote</topic><topic>Histocompatibility Antigens Class I - genetics</topic><topic>Histocompatibility Testing</topic><topic>HLA-A Antigens - genetics</topic><topic>HLA-B Antigens - genetics</topic><topic>HLA-C Antigens - genetics</topic><topic>Humans</topic><topic>Introns</topic><topic>Molecular Sequence Data</topic><topic>Mutation</topic><topic>new HLA class I alleles</topic><topic>Polymorphism, Genetic</topic><topic>Recombination, Genetic</topic><toplevel>online_resources</toplevel><creatorcontrib>Alonso-Nieto, M.</creatorcontrib><creatorcontrib>García-Sánchez, F.</creatorcontrib><creatorcontrib>Lillo, R.</creatorcontrib><creatorcontrib>Balas, A.</creatorcontrib><creatorcontrib>Blanco, L.</creatorcontrib><creatorcontrib>Aviles-Egea, M.J.</creatorcontrib><creatorcontrib>Zarapuz, L.</creatorcontrib><creatorcontrib>Vicario, J.L.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Tissue antigens</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Alonso-Nieto, M.</au><au>García-Sánchez, F.</au><au>Lillo, R.</au><au>Balas, A.</au><au>Blanco, L.</au><au>Aviles-Egea, M.J.</au><au>Zarapuz, L.</au><au>Vicario, J.L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Four new HLA class I alleles in Cauacasoids</atitle><jtitle>Tissue antigens</jtitle><addtitle>Tissue Antigens</addtitle><date>2005-07</date><risdate>2005</risdate><volume>66</volume><issue>1</issue><spage>51</spage><epage>53</epage><pages>51-53</pages><issn>0001-2815</issn><eissn>1399-0039</eissn><abstract>: Four new HLA classical class I alleles in the three loci are described in Caucasian individuals. A*3012 was first suspected by an abnormal serologic pattern that would be explained by the single amino acid substitution at the A30‐specific Ser17. B*270505 differs from B*270502 in a silent substitution at an up to now constant position in the B locus. B*3541 encodes for a new Cys at position 118 that has not been encountered in neither human nor primate alleles. Cw*0716 seems to be originated by a large‐scale interallelic recombination event between Cw*0701/*0706/*0718 and Cw*020202, giving rise to a new antigen‐binding cleft conformation.</abstract><cop>Oxford, UK; Malden, USA</cop><pub>Munksgaard International Publishers</pub><pmid>15982258</pmid><doi>10.1111/j.1399-0039.2005.00421.x</doi><tpages>3</tpages></addata></record> |
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| subjects | A3012 Alleles Amino Acid Sequence B270505 B3541 Base Sequence Cw0716 Cysteine - genetics European Continental Ancestry Group Genes, MHC Class I - genetics Heterozygote Histocompatibility Antigens Class I - genetics Histocompatibility Testing HLA-A Antigens - genetics HLA-B Antigens - genetics HLA-C Antigens - genetics Humans Introns Molecular Sequence Data Mutation new HLA class I alleles Polymorphism, Genetic Recombination, Genetic |
| title | Four new HLA class I alleles in Cauacasoids |
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