Long-term outcome of meningococcal sepsis-associated acute renal failure

Twenty-one of 209 children admitted to the intensive care unit with meningococcal septicemia developed oliguric acute renal failure necessitating renal replacement therapy. Twelve survivors underwent renal assessment at a median of 4.2 yrs postpresentation. Two had abnormal glomerular filtration rate, proteinuria, and hypertension; one had isolated proteinuria; and one had an isolated renal parenchymal defect on DMSA scan. Long-term follow-up of this population is recommended.