Bisphenol-A induces cell cycle delay and alters centrosome and spindle microtubular organization in oocytes during meiosis

Bisphenol-A (BPA) is a widely used environmental estrogen-like chemical that has a weak estrogenic activity. This study aimed to test the potential inhibitory effects of BPA on meiotic cell cycle progression, centrosomes and spindle integrity in mouse cumulus–oocyte complexes (COCs). They were expos...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular human reproduction 2005-06, Vol.11 (6), p.389-396
Hauptverfasser:	Can, A., Semiz, O., Cinar, O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Benzhydryl Compounds Biological and medical sciences bisphenol-A Cell Cycle - drug effects Centrosome - drug effects Centrosome - metabolism centrosome abnormality Embryology: invertebrates and vertebrates. Teratology Estrogens, Non-Steroidal - pharmacology Female Fundamental and applied biological sciences. Psychology Meiosis - drug effects meiotic spindle Mice Microtubules - drug effects Microtubules - metabolism oocyte Oocytes - drug effects Oocytes - metabolism pericentrin Phenols - pharmacology Spindle Apparatus - drug effects Spindle Apparatus - ultrastructure
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!