Globus pallidus deep brain stimulation in dystonia

Globus pallidus deep brain stimulation in dystonia

Globus pallidus deep brain stimulation (GPi‐DBS) is a useful alternative in the treatment of dystonia. Patients selected for GPi‐DBS were prospectively rated with the Unified Dystonia Rating Scale (UDRS). Also, “blinded” videotape assessments were performed. Eleven patients were identified. Compared...

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Veröffentlicht in:Movement disorders 2006-05, Vol.21 (5), p.692-695
Hauptverfasser: Diamond, Alan, Shahed, Joohi, Azher, Shaheda, Dat-Vuong, Kevin, Jankovic, Joseph
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Biological and medical sciences
Child
deep brain stimulation
Deep Brain Stimulation - methods
Diseases of striated muscles. Neuromuscular diseases
dystonia
Dystonia - pathology
Dystonia - therapy
Female
Follow-Up Studies
Globus Pallidus
Humans
Male
Medical sciences
Middle Aged
Nervous system (semeiology, syndromes)
Nervous system as a whole
Neurology
Severity of Illness Index
surgery
Treatment Outcome
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Zusammenfassung:Globus pallidus deep brain stimulation (GPi‐DBS) is a useful alternative in the treatment of dystonia. Patients selected for GPi‐DBS were prospectively rated with the Unified Dystonia Rating Scale (UDRS). Also, “blinded” videotape assessments were performed. Eleven patients were identified. Compared with pre‐DBS scores, there were improvements in mean total UDRS score (15.3%) and in the following subscores: neck (18.18%), trunk (32.9%), arm(17.9%), and leg (19.9%). One patient developed a skin infection and erosion requiring surgical debridement. GPi‐DBS is a safe and effective treatment for generalized dystonia in patients who remained impaired, despite optimal medical therapy. © 2005 Movement Disorder Society
ISSN:0885-3185
1531-8257
DOI:10.1002/mds.20767