Changes in brain natriuretic peptide levels and bioelectrical impedance measurements after treatment with high-dose furosemide and hypertonic saline solution versus high-dose furosemide alone in refractory congestive heart failure : A double-blind study

Changes in brain natriuretic peptide levels and bioelectrical impedance measurements after treatment with high-dose furosemide and hypertonic saline solution versus high-dose furosemide alone in refractory congestive heart failure : A double-blind study

The aim of this study was to evaluate the effect of a new treatment for refractory congestive heart failure (CHF) on brain natriuretic peptide (BNP) plasma levels and hydration station. The study was aimed at evaluating the effects of the combination of high-dose furosemide and small-volume hyperton...

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Veröffentlicht in:Journal of the American College of Cardiology 2005-06, Vol.45 (12), p.1997-2007
Hauptverfasser: PATERNA, Salvatore, DI PASQUALE, Pietro, PARRINELLO, Gaspare, FORNACIARI, Ersilia, DI GAUDIO, Francesca, FASULLO, Sergio, GIAMMANCO, Marco, SARULLO, Filippo M, LICATA, Giuseppe
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Aged, 80 and over
Biological and medical sciences
Body mass index
Cardiology
Cardiology. Vascular system
Diuretics - administration & dosage
Dose-Response Relationship, Drug
Double-Blind Method
Drug therapy
Drug Therapy, Combination
Electric Impedance
Female
Follow-Up Studies
Furosemide - administration & dosage
Heart
Heart Failure - blood
Heart Failure - drug therapy
Heart Failure - physiopathology
Heart failure, cardiogenic pulmonary edema, cardiac enlargement
Hospitalization
Humans
Male
Medical sciences
Middle Aged
Mortality
Natriuretic Peptide, Brain - blood
Natriuretic Peptide, Brain - drug effects
Rodents
Saline Solution, Hypertonic - administration & dosage
Time Factors
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Zusammenfassung:The aim of this study was to evaluate the effect of a new treatment for refractory congestive heart failure (CHF) on brain natriuretic peptide (BNP) plasma levels and hydration station. The study was aimed at evaluating the effects of the combination of high-dose furosemide and small-volume hypertonic saline solution (HSS) in refractory CHF patients. A total of 94 patients (34 women/60 men) with refractory CHF (age 55 to 80 years) were enrolled. They had to have an ejection fraction
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2005.01.059