Histopathological features of liver and its relation to serum transaminase levels in 91 cases of anti-HBe-positive chronic hepatitis B

Summary For assessing the histopathological features and its relation to alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels in anti‐HBe‐positive chronic hepatitis B in Babol, north of Iran, liver biopsy samples of 91 anti‐HBe‐positive chronic hepatitis B virus (HBV) infection with raised ALT were scored according to histological hepatitis activity index (HAI) from March 2000 to July 2003. Seventy‐seven males and 14 females with a mean age of 32.24 (±11.92) years were studied. Mean ALT and AST levels were 112.5 (±98.9) and 69.57 (±60.6) IU/l, respectively. Minimal, mild, moderate and severe chronic hepatitis were seen in 35 (38.5%), 49 (53.8%), seven (7.7%) and 0 cases, respectively. There was not any significant difference between HAI and ALT levels of