Droplet-Based DNA Purification in a Magnetic Lab-on-a-Chip

Droplet-Based DNA Purification in a Magnetic Lab-on-a-Chip

Merge, mix, split, and transport are the main manipulation steps used for on‐chip droplet‐based DNA purification (see figure). The system is able to extract genomic material from dilute raw cell samples by using the actuation of magnetic microparticles within the droplets through a matrix of coils....

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Veröffentlicht in:Angewandte Chemie International Edition 2006-05, Vol.45 (19), p.3062-3067
Hauptverfasser: Lehmann, Ulrike, Vandevyver, Caroline, Parashar, Virendra K., Gijs, Martin A. M.
Format: Artikel
Sprache:eng
Schlagworte:
DNA
DNA - genetics
DNA - isolation & purification
Equipment Design
fluorescence
Lab-On-A-Chip Devices
magnetic particles
Magnetics
Microchip Analytical Procedures - methods
microfluidics
Microfluidics - instrumentation
Microfluidics - methods
Particle Size
Silicon Compounds - chemistry
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Beschreibung
Zusammenfassung:Merge, mix, split, and transport are the main manipulation steps used for on‐chip droplet‐based DNA purification (see figure). The system is able to extract genomic material from dilute raw cell samples by using the actuation of magnetic microparticles within the droplets through a matrix of coils.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200503624