The Apoptosome: Physiological, Developmental, and Pathological Modes of Regulation

Apoptosis, a form of programmed cell death, is executed by a family of zymogenic proteases known as caspases, which cleave an array of intracellular substrates in the dying cell. Many proapoptotic stimuli trigger cytochrome c release from mitochondria, promoting the formation of a complex between Ap...

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Veröffentlicht in:Developmental cell 2006-05, Vol.10 (5), p.549-561
Hauptverfasser: Schafer, Zachary T., Kornbluth, Sally
Format: Artikel
Sprache:eng
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