Management of Essential Thrombocythemia: Implications of the Medical Research Council Primary Thrombocythemia 1 Trial

Management of Essential Thrombocythemia: Implications of the Medical Research Council Primary Thrombocythemia 1 Trial

ABSTRACT There has been a dearth of prospective randomized studies in essential (or primary) thrombocythemia (ET). To date, only two reports have been published. Cortelazzo et al reported the first study in 1995. The second is the Medical Research Council Primary Thrombocythemia 1 trial (MRC PT-1),...

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Veröffentlicht in:Seminars in thrombosis and hemostasis 2006-04, Vol.32 (3), p.283-288
1. Verfasser: Harrison, Claire N
Format: Artikel
Sprache:eng
Schlagworte:
Disease Management
Humans
Hydroxyurea - therapeutic use
Quinazolines - therapeutic use
Randomized Controlled Trials as Topic
Thrombocythemia, Essential - complications
Thrombocythemia, Essential - therapy
Treatment Outcome
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Zusammenfassung:ABSTRACT There has been a dearth of prospective randomized studies in essential (or primary) thrombocythemia (ET). To date, only two reports have been published. Cortelazzo et al reported the first study in 1995. The second is the Medical Research Council Primary Thrombocythemia 1 trial (MRC PT-1), the results and implications of which are the subject of this article.
ISSN:0094-6176
1098-9064
DOI:10.1055/s-2006-939440