Granulocyte‐colony stimulating factor producing urothelial carcinoma of renal pelvis

We report a case of granulocyte‐colony stimulating factor (G‐CSF) producing urothelial carcinoma of the renal pelvis in a 39‐year old man. The patient was admitted to Kobe University Hospital, Kobe, Japan, complaining of macrohematuria and a 6‐month history of left abdominal swelling. Abdominal comp...

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Veröffentlicht in:International journal of urology 2005-05, Vol.12 (5), p.500-502
Hauptverfasser: TERAO, SHUJI, YAMADA, YUJI, SHIRAKAWA, TOSHIRO, HARA, ISAO, KANOMATA, NAOKI, KAMIDONO, SADAO
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container_issue 5
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container_title International journal of urology
container_volume 12
creator TERAO, SHUJI
YAMADA, YUJI
SHIRAKAWA, TOSHIRO
HARA, ISAO
KANOMATA, NAOKI
KAMIDONO, SADAO
description We report a case of granulocyte‐colony stimulating factor (G‐CSF) producing urothelial carcinoma of the renal pelvis in a 39‐year old man. The patient was admitted to Kobe University Hospital, Kobe, Japan, complaining of macrohematuria and a 6‐month history of left abdominal swelling. Abdominal computed tomography showed a large mass in the left kidney and para‐aortic lymph node enlargement. A remarkable degree of leukocytosis was detected without any acute infectious disease. Enzyme immunoassay of the serum demonstrated a remarkable high concentration of G‐CSF. The patient underwent left nephroureterectomy and para‐aortic lymphadenectomy. Histochemical examination revealed urothelial carcinoma. Immunohistochemical staining with an anti‐G‐CSF antibody demonstrated G‐CSF secreting cells. The patient died 8 weeks after the surgical operation. To our knowledge, this is the second case of G‐CSF producing urothelial carcinoma of renal pelvis reported in the English literature.
doi_str_mv 10.1111/j.1442-2042.2005.01084.x
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source Wiley Online Library - AutoHoldings Journals; MEDLINE
subjects Adult
Biomarkers, Tumor - blood
Carcinoma, Transitional Cell - diagnosis
Carcinoma, Transitional Cell - secretion
Carcinoma, Transitional Cell - surgery
Diagnosis, Differential
Fatal Outcome
Granulocyte Colony-Stimulating Factor - blood
granulocyte‐colony stimulating factor producing
Humans
Immunohistochemistry
Kidney Neoplasms - diagnosis
Kidney Neoplasms - secretion
Kidney Neoplasms - surgery
Kidney Pelvis
Male
Nephrectomy
renal pelvis
Tomography, X-Ray Computed
Urography
urothelial carcinoma
title Granulocyte‐colony stimulating factor producing urothelial carcinoma of renal pelvis
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