Changes in distribution patterns of integrins in endometrium in copper T380 intrauterine device users

Intrauterine contraception is the most cost-effective reversible method of contraception today, but its mechanism of action is not well understood. Our objective was to investigate immunohistochemical distribution patterns of αv, α3, β1 integrins in women using a copper T380 intrauterine device (IUD...

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Veröffentlicht in:Acta histochemica 2005-01, Vol.107 (2), p.95-103
Hauptverfasser: Oruç, Semra, Vatansever, H. Seda, Karaer, Öznur, Eskicioğlu, Fatma, Narlıkuyu, Burcu
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Sprache:eng
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Zusammenfassung:Intrauterine contraception is the most cost-effective reversible method of contraception today, but its mechanism of action is not well understood. Our objective was to investigate immunohistochemical distribution patterns of αv, α3, β1 integrins in women using a copper T380 intrauterine device (IUD) for different periods of time to obtain insight into the role of integrins in intrauterine contraception. Endometrial biopsies were obtained from patients using T Cu380A IUD in follicular and luteal phases and in menopausal women grouped according to the period of time of IUD use (group 1:
ISSN:0065-1281
1618-0372
DOI:10.1016/j.acthis.2005.01.001