Adult height of prepubertal short children born small for gestational age treated with GH

Adult height of prepubertal short children born small for gestational age treated with GH

Objective: Human GH (hGH) treatment leads to catch-up growth in children with short stature born small for gestational age (SGA). However, long-term efficacy and safety results in this patient group remain scarce. The present study assessed the efficacy and safety of late childhood treatment with bi...

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Veröffentlicht in:European journal of endocrinology 2005-06, Vol.152 (6), p.835-843
Hauptverfasser: Rosilio, Myriam, Carel, Jean-Claude, Ecosse, Emmanuel, Chaussainon, Jean-Louis
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Blood Glucose - metabolism
Body Height - drug effects
Bone Development - drug effects
Child
Clinical Studies
Endocrinopathies
Female
Fundamental and applied biological sciences. Psychology
Glycated Hemoglobin A - metabolism
Human Growth Hormone - therapeutic use
Humans
Infant, Newborn
Infant, Small for Gestational Age - growth & development
Infant, Small for Gestational Age - metabolism
Insulin-Like Growth Factor I - metabolism
Linear Models
Male
Medical sciences
Parents
Vertebrates: endocrinology
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Zusammenfassung:Objective: Human GH (hGH) treatment leads to catch-up growth in children with short stature born small for gestational age (SGA). However, long-term efficacy and safety results in this patient group remain scarce. The present study assessed the efficacy and safety of late childhood treatment with biosynthetic hGH (Humatrope) in a group of short children born SGA (height
ISSN:0804-4643
1479-683X
DOI:10.1530/eje.1.01916