Diabetic Nephropathy in Pregnancy: Suboptimal Hypertensive Control Associated With Preterm Delivery

Nephropathy complicates 5% to 10% of pregnancies in women with diabetes and is associated with adverse outcomes. Given the importance of blood pressure (BP) control in reducing cardiovascular and renal complications outside of pregnancy, we hypothesized that poorly controlled hypertension in early pregnancy among women with diabetic nephropathy would be associated with adverse outcomes. To examine the impact of hypertensive control in early pregnancy on perinatal outcomes, we performed a retrospective cohort study of pregnancies complicated by diabetic nephropathy with “Above Target” mean arterial pressure (≥100 mm Hg; N = 21) and “Below Target” mean arterial pressure (