Development of a Lectin Microarray for the Rapid Analysis of Protein Glycopatterns

Glycosylation plays a role in a wide variety of biological processes including bacterial pathogenesis, tumor cell metastasis and inflammation. Despite the importance of carbohydrates, few techniques exist for the rapid and systematic evaluation of protein glycosylation. This paper describes a lectin...

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Veröffentlicht in:Chembiochem : a European journal of chemical biology 2005-06, Vol.6 (6), p.985-989
Hauptverfasser: Pilobello, Kanoelani T, Krishnamoorthy, Lakshmipriya, Slawek, Deepika, Mahal, Lara K
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container_title Chembiochem : a European journal of chemical biology
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creator Pilobello, Kanoelani T
Krishnamoorthy, Lakshmipriya
Slawek, Deepika
Mahal, Lara K
description Glycosylation plays a role in a wide variety of biological processes including bacterial pathogenesis, tumor cell metastasis and inflammation. Despite the importance of carbohydrates, few techniques exist for the rapid and systematic evaluation of protein glycosylation. This paper describes a lectin microarray for the rapid analysis of protein glycopatterns (see scheme).
doi_str_mv 10.1002/cbic.200400403
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source MEDLINE; Wiley Online Library All Journals
subjects analytical methods
carbohydrates
Carbohydrates - chemistry
Genetic Techniques
Glycolipids - chemistry
glycomics
Glycoproteins - analysis
Glycoproteins - chemistry
Glycoproteins - genetics
Glycosylation
lectin
Lectins - chemistry
Lectins - genetics
microarrays
Microscopy, Fluorescence
Oligonucleotide Array Sequence Analysis
Protein Array Analysis - methods
title Development of a Lectin Microarray for the Rapid Analysis of Protein Glycopatterns
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