Development of a Lectin Microarray for the Rapid Analysis of Protein Glycopatterns

Glycosylation plays a role in a wide variety of biological processes including bacterial pathogenesis, tumor cell metastasis and inflammation. Despite the importance of carbohydrates, few techniques exist for the rapid and systematic evaluation of protein glycosylation. This paper describes a lectin...

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Veröffentlicht in:Chembiochem : a European journal of chemical biology 2005-06, Vol.6 (6), p.985-989
Hauptverfasser: Pilobello, Kanoelani T, Krishnamoorthy, Lakshmipriya, Slawek, Deepika, Mahal, Lara K
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Sprache:eng
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Zusammenfassung:Glycosylation plays a role in a wide variety of biological processes including bacterial pathogenesis, tumor cell metastasis and inflammation. Despite the importance of carbohydrates, few techniques exist for the rapid and systematic evaluation of protein glycosylation. This paper describes a lectin microarray for the rapid analysis of protein glycopatterns (see scheme).
ISSN:1439-4227
1439-7633
1439-4227
DOI:10.1002/cbic.200400403