The role of pre-emptive re-transplant in graft and recipient outcome

Background. The effect of the pre-emptive re-transplant, and of inter-transplant waiting time generally, on graft and recipient survival is not well established. Methods. Analysis of the United States Renal Data System (USRDS) data (1/1/90 through 12/31/00; n = 92 844) was performed. Cox regression...

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Veröffentlicht in:	Nephrology, dialysis, transplantation dialysis, transplantation, 2006-05, Vol.21 (5), p.1355-1364
Hauptverfasser:	Goldfarb-Rumyantzev, Alexander S., Hurdle, John F., Baird, Bradley C., Stoddard, Greg, Wang, Zhi, Scandling, John D., Barenbaum, Lev L., Cheung, Alfred K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age Factors Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Child Emergency and intensive care: renal failure. Dialysis management Female Graft Rejection - surgery Graft Survival Humans Immunomodulators Intensive care medicine Kidney Transplantation - adverse effects Kidney Transplantation - mortality Kidney Transplantation - statistics & numerical data Male Medical sciences Middle Aged Multivariate Analysis Pharmacology. Drug treatments pre-emptive transplant Probability Prognosis Proportional Hazards Models re-transplant Registries Reoperation - statistics & numerical data Retrospective Studies Sex Factors Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the urinary system Survival Analysis Time Factors Tissue and Organ Procurement transplant graft survival transplant recipient survival Treatment Outcome Waiting Lists
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Zusammenfassung:	Background. The effect of the pre-emptive re-transplant, and of inter-transplant waiting time generally, on graft and recipient survival is not well established. Methods. Analysis of the United States Renal Data System (USRDS) data (1/1/90 through 12/31/00; n = 92 844) was performed. Cox regression was used to analyse time to event, with an additional analysis to stratify by transplant era. Results. Having a prior transplant, as well as the total number of transplants, was related to an increased risk of graft failure [hazard ratio (HR) 1.24, P
ISSN:	0931-0509 1460-2385
DOI:	10.1093/ndt/gfk061