Rhodium-Catalyzed Tandem Vinylcyclopropanation of Strained Alkenes

Rhodium-Catalyzed Tandem Vinylcyclopropanation of Strained Alkenes

This communication reports an unusual rhodium-catalyzed 1,6-addition of a dienylboronate ester to highly strained alkenes. The resulting vinylcyclopropane-fused tricyclic products were produced in moderate to good yields. Preliminary mechanistic studies are also presented.

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Veröffentlicht in:Journal of the American Chemical Society 2006-04, Vol.128 (16), p.5338-5339
Hauptverfasser: Tseng, Nai-Wen, Mancuso, John, Lautens, Mark
Format: Artikel
Sprache:eng
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Zusammenfassung:This communication reports an unusual rhodium-catalyzed 1,6-addition of a dienylboronate ester to highly strained alkenes. The resulting vinylcyclopropane-fused tricyclic products were produced in moderate to good yields. Preliminary mechanistic studies are also presented.
ISSN:0002-7863
1520-5126
DOI:10.1021/ja060877j