Lung cancer as an immune reconstitution disease in an HIV-1 positive man receiving HAART

A case of small-cell lung cancer with prompt worsening of the clinical course was observed in a patient with significant immune restoration after receiving effective highly active antiretroviral therapy (HAART) for seven months. Rapid and enormous enlargement of metastatic liver was the main symptom...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Postȩpy higieny i medycyny doświadczalnej 2006, Vol.60, p.181-183
Hauptverfasser:	Knysz, Brygida, Zalewska, Małgorzata, Rzeszutko, Marta, Gładysz, Andrzej
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antiretroviral Therapy, Highly Active Carcinoma, Small Cell - drug therapy Carcinoma, Small Cell - immunology Carcinoma, Small Cell - secondary Fatal Outcome HIV Seropositivity - complications HIV Seropositivity - drug therapy HIV Seropositivity - immunology Humans Lamivudine - administration & dosage Liver Neoplasms - secondary Lung Neoplasms - immunology Lymphatic Metastasis Male Ritonavir - administration & dosage Saquinavir - administration & dosage Zidovudine - administration & dosage
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	A case of small-cell lung cancer with prompt worsening of the clinical course was observed in a patient with significant immune restoration after receiving effective highly active antiretroviral therapy (HAART) for seven months. Rapid and enormous enlargement of metastatic liver was the main symptom. Chest x-ray showed an enlargement of the left hilus. The patient died 22 days after the onset of the fulminant disease. We suggest that the occurrence and aggressive course of the lung cancer resulted from the development of immune reconstitution syndrome.
ISSN:	1732-2693